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[16] [17] Given that GLP-1 medications slow gastric emptying, adequate fibre and hydration help prevent constipation, a common side effect

Common adverse effects across these medications include nausea, vomiting, diarrhea, and constipation, along with more serious risks such as thyroid C-cell tumors (in animal studies), pancreatitis, and gallbladder disease

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While peptides are a broad category of amino acid-based drugs that include well-known legal ones (like insulin and the GLP-1 weight loss drugs), the buzzand the FDA panelis focused on a bunch of them known by a string of letters and numbers

GLP-1 medications work by mimicking the effects of the GLP-1 hormone, which is produced within the small intestine

However, the skin barrier limits the transdermal absorption rate, and simple topical application is difficult to significantly increase the oxidation rate of fatty acids throughout the body or locally