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Lactate stimulates vasculogenic stem cells via the thioredoxin system and engages an autocrine activation loop involving hypoxia-inducible factor 1

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1 Departamento de Biologa Molecular, Instituto Universitario de Biologa Molecular IUBM-UAM and Centro de Biologa Molecular Severo Ochoa (UAM-CSIC), Madrid, Spain, 2 CIBER de Enfermedades Cardiovasculares, ISCIII (CIBERCV), Madrid, Spain, 3 Instituto de Investigacin Sanitaria La Princesa, Madrid, Spain

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