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One of these studies also failed to identify any change in anxiety-like behavior 162 , while two further studies employing exendin-4 observed an anxiogenic effect following acute administration 158,169
A.NgC.et al (2016)
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These include nausea, vomiting, diarrhoea, abdominal pain, and constipation, which typically occur during dose initiation or escalation and often diminish over time as the body adjusts to the medication
Data across multiple trials consistently shows that dual agonists (GLP-1 plus GIP) produce lower nausea rates than GLP-1-only compounds
Food and Drug Administration (FDA) in 2017 for the treatment of adults with type 2 diabetes mellitus
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