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This process produces ketone bodies (acetoacetate, beta-hydroxybutyrate, and acetone), which are partially excreted in urine and can impart a distinctive sweet or fruity odor
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This dual-action mechanism is why tirzepatide is often referred to in medical literature as a twincretin. The development of a molecule that could successfully activate both pathways without significant safety concerns took years of laboratory research before it ever reached human trials
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