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Some patients notice initial improvements in mental clarity, focus, or learning capacity within 1-2 weeks as synaptic formation begins

In addition, differences in the initial situation of gastric emptying, which is a measure of the effectiveness of GLP- 1- receptor co-agonists, are likely to have a different effect on patients with obesity than on people in whom preoperative intragastric food retention after taking GLP- 1 receptor co-agonists is not impaired, and in people with diabetes [127]

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Du et al

The ceiling looks the same as it did at midnight

World Psychiatry 13 , 411 (2014)