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Semaglutide (subcutaneous route): Description and use
Additive effect on kidney outcomes including macroalbuminuria was also expected from AMPLITUDE-O substudy, however, additive effect of semaglutide and SGLT2i on the composite kidney outcomes without macroalbuminuria was not indicated in the FLOW substudy [50]
Importantly, only Semaglutide and Tirzepatide are FDA-approved and available todayRetatrutide remains investigational, with realistic approval falling between the second half of 2027 and mid-2028
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