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Common Side Effects These occur in many patients using tirzepatide: Nausea Diarrhea Decreased appetite Stomach pain Constipation Serious but Rare Side Effects These occur in less than 1% of patients: Severe allergic reactions Pancreatitis (pancreas inflammation) Gallbladder problems Vision problems Kidney problems Thyroid tumors (only seen in animal studies) Patients using compounded versions may experience additional side effects due to contamination or dosing inconsistencies that would not occur with FDA-approved formulations

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Losing a significant amount of weight alters how the body distributes pressure across the spine

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If you are supplementing sodium properly, chloride typically comes along with it