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Maintenance dosing considerations: Community protocols commonly describe two maintenance approaches after the initial 8-12 week loading phase: (1) reduced frequency at the same dose (e.g., IV once monthly instead of weekly), or (2) transitioning from injectable/IV to high-bioavailability oral (liposomal) for convenience while accepting a modest reduction in peak levels

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It is also increasingly recognized for its role in the microbiome, where it influences gut health and microbial balance, further extending its biological functions [20]