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Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntingtons disease

Mice were single housed 1 week before surgery and metabolic tests started after a recovery period of 3 weeks

thus, its loss may exacerbate metabolic adaptation and increase vulnerability to rebound weight gain following treatment discontinuation

Regular physical activity, particularly resistance training and moderate-to-vigorous exercise, may enhance GLP-1 levels and improve metabolic health

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