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Glucose-6-phosphate dehydrogenase (G6PD) deficiency: High doses of vitamin C in CB 12 injection could cause hemolysis, a condition where red blood cells are destroyed prematurely, in patients with G6PD deficiency

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Skin sensitivity: an emerging signal Skin burning and abnormal touch sensitivity (dysesthesia) appears as a dose-related, reversible signal in two case series and post-market surveillance. Trials did not pre-specify it, and the tirzepatide label does not list it

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