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There were several study limitations identified by the researchers

GLP-1 receptor agonists have a well-established safety profile backed by years of clinical research and widespread real-world use

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While studies are scarce, it seems rapid weight loss by any means can have an effect on your feet

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However, some side effects can include: Nausea Heartburn Headaches Constipation Diarrhea These side effects are most common when first starting GLP #1 or GLP #2 injections or increasing dosages of these medications