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These are mechanistic observations within experimental systems, not claims about human physiology
One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes
Approximately 90% of GLP-1 is metabolized by DPP-4 before reaching the central venous circulation (Holst and Deacon, 2005), and the peak circulating concentration of active GLP-1 (7-36)NH 2 after a meal in healthy subjects is usually less than 10 pmol/L due to the rapid degradation of DPP-4 (Bak et al., 2014)
Time-saver: Physicians report cutting pharmacy call-backs by 30-45 minutes per clinic day
Ogura, M
In: Progress in Mountain Medicine and High Altitude Physiology
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