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Long-term scalp safety data is not yet available, so prescribers should use latanoprost as a targeted addition rather than a standalone therapy

Tosukhowong P, Boonla C, Dissayabutra T, Kaewwilai L, Muensri S, Chotipanich C, et al

Moreover, the inhibition of SLC7A11 or GPX4 has been shown to enhance IR sensitivity in radioresistant cancer cells and xenografts [152]

Interestingly, the oocyte maturation was blocked at a very specific development stage (metaphase I arrest) where a sensor for DNA damage (Spindle Assembly Check point/Dna Damage Response) assesses the DNA integrity and blocks the oocyte maturation through the activation of a protein (ATM kinase)

Sikiric et al., 1993b