Journal of Clinical Epidemiology, 47, 10216
A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 g per day per os (p.o.) for 8 weeks (form not reported)
This is the mechanism behind semaglutide, tirzepatide, and every other GLP-1 agonist on the market
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Those three amino acids are bonded to a copper(II) ion, and together they form a naturally occurring compound found in human blood plasma, saliva, and urine