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That promotes lipolysis (fat breakdown) particularly in visceral fat deposits, while preserving subcutaneous fat and lean muscle mass
[14] [41] In December 2025, the FDA approved an oral version of semaglutide for weight management, using the same brand name (Wegovy) as the injectable version
But real-world stories tell a different tale
Under medical supervision, this dual mechanism may help: Side effects are usually mild, occur early in treatment, and reduce as the dose is titrated gradually
came to similar conclusions, finding that GLP-1 agonists were able to increase BMD and reduce fracture risk compared to other diabetes drugs
The STEP 1 extension found that the cardiometabolic improvements seen during treatment including blood sugar, blood pressure and cholesterol largely reverted toward baseline within a year of stopping
