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For some people, you may not need the highest dose for weight loss maintenance

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Current understanding is predominantly based on animal experiments

Most studies do also report a wide range of negative side effects including nausea and vomiting

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In practical terms, low energy availability may contribute to: Slower muscle and tendon remodeling Reduced tolerance to training volume Delayed strength progression during rehabilitation Higher perceived fatigue Increased risk of overuse symptoms Longer timelines to return to sport at full performance capacity For physical therapists and sports medicine clinicians, this matters more than ever