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Nature 483 , 218221 (2012)
Inflammatory and Cytokine Signaling Genes: In cell culture models of inflammation (e.g., LPS-stimulated macrophages or keratinocytes), GHK-Cu has been investigated for its capacity to suppress the expression of pro-inflammatory cytokines like IL-6 and TNF-
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This finding challenges the assumption that targeting oxidative stress alone is sufficient to ameliorate ASD-like phenotypes, particularly when interventions are applied after critical neurodevelopmental windows