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Muscle preservation: Because AOD 9604 targets adipose tissue specifically and does not suppress systemic anabolic signaling, researchers have hypothesized that it may allow for fat loss with less collateral impact on lean mass, though this has not been formally tested in head-to-head trials

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Redness, itching, or mild irritation at the application site can occur, particularly during initial use or with higher concentrations

Researchers can experiment to find what works best for their situation

Some researchers use exfoliating treatments periodically to further improve absorption

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