10.1002/jcb.20705 J Cell Biochem
These include: Oxidative stress: One of the more recent studies on DSIP, from 2011, concluded that the peptide has a strong antioxidant effect owing to an ability to activate the (rat) bodys natural mechanisms against oxidative stress.21 Edema (swelling via fluid buildup): Again in rats, a 1992 study suggested that DSIP may have an antiedematic effect related to the activation of the GABAergic system and inhibition of serotonin, noradrenaline, and histamine systems.22 Convulsions: Two rodent studies in the 1990s support DSIPs use as an anticonvulsant
These symptoms are more likely when treatment starts, after a dose increase, or after eating large, fatty or rich meals
Brendan Camp is a double board-certified dermatologist in dermatology and dermatopathology at MDCS Dermatology: Medical Dermatology & Cosmetic Surgery
As of 2025, retatrutide is still in Phase 3 clinical trials
What are the potential long-term effects of blood clot-related injuries from Wegovy