doi: 10.1186/s40104-021-00545-7 362 HuangJChenBLiHZengQHWangJJLiuHet al
These antibodies are used to treat a variety of solid and blood tumors and include anti-CTLA-4 antibodies (ipilimumab), anti-PD-1 antibodies (nivolumab, pembrolizumab), and anti-PD-L1 antibodies (atezolizumab, durvalumab, avelumab)
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The high dose also improved oral glucose tolerance, suppressed hyperinsulinemia, and cut microvesicular liver steatosis by 73%
El tratamiento puede reanudarse, por lo general a una dosis menor, cuando la toxicidad cutnea haya disminuido, siguiendo un estricto control clnico