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56 OuM.JiangY.JiY.ZhouQ.DuZ.ZhuH.et al (2022)

Participants also recorded reductions in waist circumference (average 7.1cm loss on 6mg, 8.2cm on 12mg, 10cm on 36mg, compared with 3.1cm loss on placebo), blood pressure (estimated -4.2 and -1mm HG difference between placebo and orforglipron in systolic and diatolic blood pressure, respectively) and cholesterol (-2.1% difference between placebo and orforglipron)

Wegovy is FDA-approved for obesity and weight loss, while Ozempic is approved for type 2 diabetes

doi:10.1080/00952990.2018.1545023

Typically, people continue on a dose of 1 mg or 2.4 mg (Wegovy) to sustain their results

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