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Also in CLL, most recent interim results of a Phase II study evaluating GS-9973, an investigational oral inhibitor of spleen tyrosine kinase (Syk), achieved an overall response rate of 49%, with an estimated progression-free survival rate of 70%, and 62% of patients achieved at least a 50% tumor reduction

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the gums, [1] cheeks or palate [2] as well as in the larynx

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