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Date of Acceptance: December 13, 2019 Abbreviations: reactive oxygen species, ROS

Where a product ships as powder, established protocols describe dissolving to a known concentration with bacteriostatic water before drawing the labeled amount

Regular sterile water contains no such preservative, so once it's punctured it should be used immediately and discarded

In summary, high ROS levels lead to irreversible damage to erythrocyte biomolecules, mainly lipids or proteins, thereby inducing eryptosis

Protective packaging minimized movement during transit

medRxiv:2022.2006.2007.22276020 Dambrova M, Liepinsh E (2015) Risks and benefits of carnitine supplementation in diabetes