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For some reason, and I can find no scientific basis for this, that recommendation was changed in 1974 to an injection every two months and then in 1984 to every three months

Most people experience noticeable benefits within 4-8 weeks of consistent use

Establishing a standardized peripheral nerve injury model in dogs that mirrors the rodent sciatic crush protocol would require significant methodological development, but the clinical relevance to intervertebral disc disease and traumatic nerve injury makes it a scientifically defensible investment of research effort

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It promotes fibroblasts and collagen production Fibroblasts are biological cells needed to maintain the structural framework of body tissues like tendons and ligaments