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The state of the candidates
Results Decreased expression of GLP-1R in the cartilage tissues of the knee OA model Western blot analysis was used to quantify the expression of GLP-1R in the knee cartilage tissue of the OA rats at various time-points after the induction of OA
The pharmaceutical industry is developing newer and potentially cheaper or more effective molecules that target GLP-1 and associated pathways (for example, the so-called dual- and triple-agonists tirzepatide, retatutride and orfoglipon) 257,258
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