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Highlights The first incretin hormone, gastric inhibitory peptide, was identified in the early 1970s, followed by the discovery of glucagonlike peptide 1 (GLP-1) in the 1980s [1]

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The chromatographic system used a binary solvent (water and methanol) system delivered as a gradient

Measured Total fat mass, compared with placebo and an approved medicine

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Since then numerous patients have been treated with high dose vitamin B12 worldwide