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acts as a copper transporter and signaling modulator in research models Focus Areas: ECM signaling, oxidative stress responses, remodeling enzymes, and gene networks Proposed Mechanisms (Research Context) ECM Modulation: Influences genes tied to collagen, elastin, and glycosaminoglycan balance

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These studies suggested GSTM2 regulated lipid metabolism specially beyond detoxification/antioxidant, the basic functions of GSTs

This work fixes a previously obscure piece of the puzzle regarding glutathiones role in ER biology and offers tantalizing prospects for disease intervention through metabolic and molecular engineering

Front Endocrinol 2021;12:626390