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We obtained the entries for the responsible metabolic enzymes from the BRaunschweig ENzyme DAtabase (BRENDA) database 81 and extracted their allosteric effector (activator and inhibitor) information and inhibitory half-saturation constants (K i ) values, as reported for Homo sapiens , Mus musculus , and Rattus norvegicus
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Conversely, it may enhance the renal excretion of some drugs, such as amphetamines and certain tricyclic antidepressants, by acidifying the urine
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