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Functionally, no-DAC CJC-1295 acts like a somewhat longer-lasting GHRH signal: it binds the pituitary GHRH receptor, a G-protein-coupled receptor that raises intracellular cyclic AMP in somatotroph cells, and pushes those cells to synthesize and release GH but only for a window measured in minutes to a couple of hours, not days

N-A-C is approved as a drug in some European jurisdictions for use in preventing liver damage from acetaminophen overdose

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It is produced exclusively through solid-phase peptide synthesis and appears as a white lyophilized powder in its research-grade form

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231 : 488493 Aureli T, Di Cocco M, Puccetti C, Ricciolini R, Scalibastri M, Miccheli A et al