Subcutaneous injection protocol: Starting dose: 200 to 300 mcg daily Titration: Increase by approximately 100 mcg every 1 to 2 weeks as tolerated Target dose: 400 to 500 mcg daily by weeks 5 through 12 Frequency: Once daily, subcutaneous Cycle length: 8 to 12 weeks, with optional extension to 16 weeks Timing: Consistent daily timing, typically evening for sleep applications Oral/sublingual protocol: Duration: 30 days Frequency: 1 to 4 cycles per year Best combined with: Exercise and nutrient-rich diet Injection sites should be rotated between the abdomen, thighs, and upper arms to prevent lipohypertrophy and ensure consistent absorption
Note that gabapentin and pregabalin have recently been classified as controlled substances
Pinch a fold of skin, insert at 45 to 90 degrees, inject slowly, hold for 5 to 10 seconds, then withdraw
Hay DL, Chen S, Lutz TA, Parkes DG, Roth JD
M.DequenneI.et al
Here's exactly how the process works and what to expect