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As discussed in the previous section, there are two enzymes of creatine synthesis, glycine amidinotransferase (encoded by the GATM gene ) and guanidinoacetate N -methyltransferase (encoded by the GAMT gene), and one major creatine transporter encoded by the SLC6A8 gene

[2] [1] For patients with neurological symptoms , hydroxocobalamin 1 mg is given intramuscularly on alternate days until no further improvement occurs, followed by maintenance injections every two months for life

Indeed, if there is a methionine deficit, homocysteine can be re-methylated to form methionine, and if there is an adequate amount of methionine, homocysteine is used to produce cysteine (161)

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