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The standard diagnostic pathway includes a serum B12 blood test as the initial screening tool

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Its use as a research tool should therefore be accompanied by target-confirmation experiments, pathway-specific metabolite monitoring, appropriate vehicle controls, lot-specific documentation, and safety endpoints matched to the study duration and biological model

Older Adults As we age, the bodys ability to absorb B12 from food diminishes, making supplementation necessary for optimal health

Gastrointestinal Laboratory