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Anecdotal reports from Phase 2 participants suggest that nausea severity is higher when dosing occurs in the early morning on an empty stomach, possibly because fasting amplifies the compound's gastric-slowing effect
Pharmacokinetic studies demonstrated approximately 38% oral bioavailability and blood-brain barrier penetration, unusual for a peptide-based compound and attributable to Dihexa's small size (504.66 Da) and hydrophobic modifications
If you are on this dose and reconstituted with 2ml, you are pulling the full 1ml in a single draw
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Current investigations are focused on understanding whether NNMT inhibition might influence cancer progression or aggressiveness
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