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This is a significant increase from when the first GLP-1 drug was approved by the Food and Drug Administration to be marketed, originally to those suffering from diabetes, in 2005
PMID 15090972
But for many, semaglutide has changed the story
This results from GLP-1 receptor activation in the brainstem's chemoreceptor trigger zone, as well as delayed gastric emptying
While the Retatrutide weight loss potential is significant, it remains in the clinical trial phase and is not yet FDA approved
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