Epub 2016 Nov 15
The picture is consistent: the adverse events are overwhelmingly gastrointestinal, they track with dose, and they cluster during escalation
Reduced Recovery Time: For individuals recovering from illness or surgery, IV therapy may help speed up the healing process by providing the body with the nutrients it needs to repair itself.
Commonly reported side effects remain mild and often transient
The study enrolled 136 adults aged 1875 years with moderate to severe active UC (mMS 4-9) who had inadequate response to conventional therapies or failure/intolerance to biologics, with participants receiving three intravenous infusions at weeks 0, 2, and 6 of either placebo, 450mg, or 850mg doses (65, 66)
The suggested regimen is crystalloid fluids equivalent to 2mL/kg/%BSA epidermal detachment per day for the first 48 hours [41] with subsequent fluid management achieving urine output greater than 1mL/kg/hour and normalisation of base excess (risk of alkalosis) and lactate