Taste receptors of the gut: emerging roles in health and disease
AD is characterized by a decade-long prodromal stage, and dementia diagnosis typically occurs in the late biological stage of AD, by which time substantial amounts of A and tau proteins have accumulated in the cortex [101]
Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes2025
To sustain intracellular oxidative balance, the Nrf2 signaling pathway and mitophagy mechanism each play a pivotal role
Dapagliflozin was the first SGLT2 inhibitor approved in the EU (2012), and canagliflozin was the first to be approved in the US (2013)
Intriguingly, studies suggest a potential role of GLP-1 RAs in pain relief, including acute and chronic pain 65 , chronic migraine 66 , and diabetic neuropathic pain 67