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This bypasses the gut as well, so absorption is better than oral
In fact, by supporting weight loss, tirzepatide may indirectly reduce the metabolic strain caused by an underactive thyroid
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Studies with the monoclonal antibody bimagrumab in combination with incretin mimetics like semaglutide or tirzepatide are ongoing to assess the affect on lean muscle mass preservation
Conversely, older adults or those with metabolic syndrome may see more gradual progress, which is still clinically meaningful
Results depend on maintenance and lifestyle
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