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53 They not only revealed a critical, albeit complex, role of claudin-2 in intestinal homeostasis, regulating epithelial permeability, inflammation, and proliferation but also suggested a potential adaptive function for the increased claudin-2 expression in IBD patients

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In mammals, LC3 is a widely observed gene related autophagy dysfunctions and serves as a marker of autophagy activity in cells (Kabeya et al., 2000)

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