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Researchers attached a fatty acid chain to the molecule, allowing it to bind to albumin, a protein that circulates in the bloodstream
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However, 38% thought it made their symptoms worse (more of those with Crohns disease than those with ulcerative colitis) although not all affected avoided it
Back O'Rahilly, S (15 April 2020' 'The islet's bridesmaid becomes the bride: Proglucagon-derived peptides deliver transformative therapies', Cell , 184, 1945-48
