semaglutide cardiovascular indication Summary of clinical use Semiglutide (Wegovy) in Overweight Non-Diabetic

It can either be used as a preventive or during flare-ups to ease symptoms

Inhibited glucagon secretion and suppressed hepatic gluconeogenesis: Glucagon is the hormone that increases blood glucose levels

4Mechanical stretch receptors in the stomach signal to the brain that the stomach is literally stretching beyond capacity and to stop eating

doi:10.4093/dmj.2012.36.2.108

Options include: Metoclopramide : May help with delayed gastric emptying but should only be used for short courses (maximum 5 days) due to risk of neurological side effects Prochlorperazine : Can be effective for nausea and vomiting Cyclizine : An alternative that works through a different mechanism Ondansetron : Sometimes used but may cause constipation Domperidone : Used cautiously due to risk of heart rhythm problems (QT prolongation), particularly in older adults, those with heart conditions, or those taking other medications affecting heart rhythm For people with diabetes, it's important to follow sick-day rules if experiencing vomiting

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