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Constipation and stomach ache were reported more frequently in the active group (10%) compared to the placebo group (3%)
NAC can be taken once or twice daily splitting the dose morning and evening provides more consistent cysteine availability for glutathione synthesis
Bacteriostatic water is preferred for multi-dose vials due to the preservative
Mild flushing or warmth shortly after dosing
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In 2014, an influential study by Wang et al
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