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Nutrition priorities: Increase protein to 1.0 to 1.2 grams per kilogram daily

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Reported effects include: Potential mood improvements associated with weight loss Isolated reports of depression and anxiety Rare cases of suicidal ideation (causal link unconfirmed) Generally low incidence in clinical trials Patients should be aware that whilst there is no official link established between these medications and serious mental health deterioration, individual responses vary considerably

This variability in bowel habits may be particularly problematic for individuals with pre-existing hemorrhoidal disease or other anorectal conditions