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This approximately 3,000 to 5,000-fold difference in half-life represents the primary pharmacological divergence between the endogenous hormone and its synthetic analog
J Clin Invest (2016) 126(3):85964
Impaired Glucoronidation: The activity of the UGT enzymes that operate the process of glucuronidation can have genetic weaknesses that impair their function
I = 38.7%, p = 0.100) (S)
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