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Fecal elimination of metabolites also occurs, particularly following oral administration, though quantitative contribution of each elimination pathway varies by route and dose
This maximizes BPC-157's local effects while ensuring TB-500's systemic benefits reach all tissues
Pharmaceutics 13 , 921 (2021)
Nausea occurs because GLP-1 activates receptors in the brainstem's chemoreceptor trigger zone (area postrema) and slows gastric emptying
& Hakkinen, K
Cullen, P
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