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Premenopausal women with functioning ovaries typically have enough estrogen production to compensate for the loss from adipose tissue, though exceptions exist, especially with very rapid or very significant weight loss

Both work by affecting hormone signals that help regulate hunger, food intake, and blood sugar levels, which may support weight reduction in some patients

Contact your GP if skin changes cause significant distress, if you experience skin breakdown or persistent redness, if weight loss consistently exceeds 1 kg weekly, or if you notice signs of nutritional deficiency such as hair loss or brittle nails

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