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Such observation could be attributed to the anti-apoptotic effect of GIP on osteoblasts (71), as osteoblast-derived hormones such as osteocalcin and lipocalcin 2 are implicated in regulating peripheral metabolism and modulate food intake (36, 72)
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Lyophilized semaglutide should be stored at -20C prior to reconstitution
Occasional hypersensitivity reactions have been observed, especially skin rashes which in some instances progressed to exfoliation
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