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The minimum BMI for semaglutide (Wegovy) under FDA labeling is 30 without any additional conditions, or 27 with at least one weight-related comorbidity such as type 2 diabetes, hypertension, or dyslipidemia

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36 Despite limited evidence, the federal drug authority (FDA) has recommended avoidance of GLP-1RA medication use among individuals who have any history of familial thyroid cancer or genetic predisposition to multiple endocrine neoplasia

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