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Consequently, knowing how to store semaglutide correctly prevents medication waste and ensures optimal treatment outcomes
However, the complexity of peptide synthesis means that demonstrating equivalence is closer to the biosimilar process than to typical small-molecule generics
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Proposed mechanisms include improvements in endothelial function, reduction in systemic inflammation, favourable effects on blood pressure and lipid profiles, and direct actions on cardiac and vascular tissues expressing GLP-1 receptors
The findings were published in JAMA Internal Medicine on January 20, showing that glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic carry an 8.2% higher risk of chronic kidney disease than sodium-glucose cotransporter-2 (SGLT2) inhibitors
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