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Constant Fatigue One of the hallmark signs of B12 deficiency is persistent fatigue

Patients with these risk factors should discuss screening and supplementation strategies with their GP, particularly if experiencing symptoms such as fatigue, paraesthesia, glossitis, or cognitive changes suggestive of deficiency

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Loren Pickart, who identified GHK in 1973, published gene-expression analyses suggesting GHK modulates a large number of human genes