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As GSH represent the primary antioxidant defense system, the reduction of GSH could influence the redox homeostasis and elevate the naturally occurring ROS levels inside the cancer cells 40
Glutathione is more directly associated with skin health because of its role as an antioxidant that reduces oxidative damage and helps regulate melanin production
Catalase (CAT) activity was measured by monitoring the decomposition of hydrogen peroxide, following the protocol described by Goth (1991), and results were reported as kU/g protein
The significance of NADPH levels to cellular survival has been demonstrated by overexpression of several cytoplasmic enzymes that synthesize NADPH leading to lifespan extension in model organisms such as Drosophila melanogaster
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